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The November 2021 issue of Reproduction contains a special editorial on Reproductive Toxicology guest edited by Dr Aileen F Keating and Dr Adam J Watkins.

This special series was designed to provide further insight into female reproductive toxicity with review papers on emerging toxicants and emerging cellular targets.

This special issue describes several aspects of reproductive toxicity and highlights where deficits remain and how specific developmental windows of exposure can be critical for the resultant outcomes.

Explore this special issue:

EDITORIAL

Reproductive Toxicology. Dr Aileen F Keating and Dr Adam J Watkins

• Emerging toxicants and cellular targets Author(s): Aileen F Keating and Adam J Watkins

 SPECIAL REVIEW

• The male mammary gland: a novel target of endocrine-disrupting chemicals Author(s): Gillian K Szabo and Laura N Vandenberg

• Effects of chemical mixtures on the ovary Author(s): Vasiliki E Mourikes and Jodi A Flaws

• Impacts of paternal environment and lifestyle on maternal health during pregnancy

Author(s): Afsaneh Khoshkerdar, Ece Eryasar, Hannah L Morgan, and Adam J Watkins

• Endocrine disruption and reproductive disorders: impacts on sexually dimorphic neuroendocrine pathways Author(s): Heather B Patisaul

• Impact of endocrine disruptors on neurons expressing GnRH or kisspeptin and pituitary gonadotropins Author(s): Troy A Roepke and Nicole C Sadlier

• Environmental exposures, fetal testis development and function: phthalates and beyond Author(s): Hui Li and Daniel J Spade

• Pregnancy exposure to endocrine disrupting chemicals: implications for women’s health Author(s): Diana K Haggerty, Kristen Upson, Diana C Pacyga, J Ebba Franko, Joseph M Braun, and Rita S Strakovsky 

Research

•  GDF-8 stimulates trophoblast cell invasion by inducing ALK5-SMAD2/3-mediated MMP2 expression Author(s): Lanlan Fang, Zhen Wang, Ze Wu, Yang Yan, Yibo Gao, Yuxi Li, Jung-Chien Cheng, and Ying-Pu Sun
• Cell signaling in sperm midpiece ensures quiescence and survival in cauda epididymisAuthor(s): Archana Devi, Bhavana Kushwaha, Jagdamba P Maikhuri, Rajender Singh, and Gopal Gupta

• Female reproductive abnormalities in mouse adolescent pregnancy Author(s): Chen Yang, Yue Li, Hai-Yang Pan, Meng-Yuan Li, Ji-Min Pan, Si-Ting Chen, Hai-Yi Zhang, Zhen-Shan Yang, Hai-Ting Dou, and Zeng-Ming Yang

• Regulation of dual specificity phosphatases by fibroblast growth factor signaling pathways in bovine granulosa cells Author(s): Lauriane Relav and Christopher A Price

• The (pro)renin receptor and soluble (pro)renin receptor in choriocarcinoma Author(s): Saije K Morosin, Sarah J Delforce, Richard G S Kahl, Celine Corbisier de Meaultsart, Eugenie R Lumbers, and Kirsty G Pringle

• GRIM19 is involved in WT1 expression and epithelial-to-mesenchymal transition in adenomyotic lesions Author(s): Chen Geng, Hao-ran Liu, Yue Zhao, Yang Yang, and Lan Chao

 Watch this video from Guest Editor, Professor Adam Watkins.