3 Year PhD Studentship, Oxford Brookes University

Dec 4, 2019

Time to be born: the role of thyroid hormones in the development of the

hypothalamic-pituitary axis before birth

3-year PhD Studentship

Nigel Groome PhD Studentship at Oxford Brookes University

Starting September 2020


Thyroid hormones and cortisol are important hormonal regulators of fetal

growth and development.  Thyroid hormone deficiency before birth delays

maturation of fetal organs and prolongs gestation, possibly via effects

on the fetal hypothalamic-pituitary-adrenal (HPA) axis.  The aim of this

PhD studentship is to investigate the mechanisms by which hypothyroidism

in utero influences the activity of the fetal HPA axis.  In

collaboration with colleagues at the Universities of Oxford and

Cambridge, the project will use immunohistochemistry to assess neuronal

networks and pituitary cell populations, and tissue culture to examine

the secretory capacity of the fetal pituitary in vitro.


For further information contact Dr Alison Forhead:



Eligibility: Home UK/EU applicants who must be permanently resident in

the UK/EU.  Applicants should have a first or upper second class honours

degree in physiology or related discipline.


Closing date: 31 December 2019


Further details: