MSCA ITN founded project “DohART-NET” focusing on effect of altered conditions during the periconceptional (PC) period of development in humans, including babies born from assisted reproduction (ART, “test-tube”) interventions, and from diabetic, obese mothers. The DohART-NET project integrates pre-clinical (animal and stem cell-models) and clinical studies and apply data linkage, bioinformatics and network science for the identification and validation of mechanisms of diseases common in early development. The project will promote efficient disease prevention and potential personalised therapeutic interventions in both the general and ART populations to overcome adverse disease pathways. DohART-NET will train 13 Early Stage Researchers (ESRs) PhD students on this important topic much needed to improve public health over several generations, and it will integrate pre-clinical, translational clinical and in silico modeling approaches. The ESRs will strongly benefit from a network of internationally recognized scientists and the participation of companies with relevant interests and expertise in the field.
DohART-NET Network: BioTalentum Ltd. (Hungary), University of Cambridge (UK), University of Manchester (UK), University of Southampton (UK), Erasmus University Medical Center (Netherlands), CeMM (Austria), Ludwig Maximilian University of Munich (Germany), MWM GmbH (Germany), Universitair Ziekenhuis Brussel (Belgium), IVI Valencia (Spain)
Job Title: PhD Position (ESR6)
Application Deadline: 14th July 2019
Recruiting Institution: University of Southampton, UK
Objectives:
The applicant will develop a multidisciplinary project focused on early pregnancy physiology. The project will utilize an established mouse model to elucidate mechanisms how maternal dietary challenge around conception induces offspring health risks. Previously, we have shown that poor nutrition exclusively around conception can increase the long-term health risks in offspring, and early markers are detectable even prior to implantation. The aim of the current project is to elucidate underlying pathways involved in induction of short- and long-term consequences including neurophysiological alterations.
The ideal candidate should have solid knowledge in molecular and cellular biology, as well as physiology, early development and proteomics. Practical experience in animal experiments, proteomics and molecular and cell biology, together with problem solving, initiative and management competences, is strongly preferred but not required.
Regular meetings and workshops within the EU-funded DohART-NET International Training Network will supplement the training and support provided at University of Southampton. The successful candidate will also benefit from work secondments in the participating academic and industrial teams.
Appointment:
The appointment will be on a temporary basis for a period of 36 months (Regular employment contract). The candidate will receive a Monthly Living Allowance plus a Mobility Allowance compliant with the applicable EC Marie Skłodowska-Curie Actions-ITN general conditions. Under UK legislation the living allowance, mobility allowance and any applicable family allowance are all deemed taxable. The gross salary calculated after Employer’s costs will then be subject to Employee’s deductions for Tax, NI and Pension contributions where applicable. The sterling salary payable will also be affected by exchange rate fluctuations and will therefore be subject to six monthly reviews.
Early Stage Researcher Salary Range: £36,958 (without family allowance) to £41,758 (with family allowance)
Eligibility:
Applicants should meet the following eligibility criteria:
- have a background in biology or related fields
- have not been awarded a PhD already
- have less than 4 years of full time – including any period of research experience at the signature of the contract
(This is measured from the date when the degree was obtained, which formally entitles the candidate to embark a doctorate, either in the country in which the degree was obtained, or in the country in which the research training is provided. Degree: MSc, MD, DVM and BSC in some countries.) - at the time of selection, the candidate must have not resided or carried out their main activity (work, studies, etc.) in the country of their host organization/recruiting institution for more than 12 months in the 3 years immediately prior to selection. Short stays such as holidays are not considered.
- excellent knowledge of the spoken and written English language
- excellent communication and team working skills
How to Apply and further details:
